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1

Conflict Resolution in the Genome: How Transcription and Replication Make It Work

Hamperl, Stephan, Cimprich, Karlene A.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.98 MB

english, 2016

2

Causes and consequences of replication stress

Zeman, Michelle K., Cimprich, Karlene A.

Journal:

Nature Cell Biology

Year:

2013

Language:

english

File:

PDF, 391 KB

english, 2013

3

Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses

Hamperl, Stephan, Bocek, Michael J., Saldivar, Joshua C., Swigut, Tomek, Cimprich, Karlene A.

Journal:

Year:

2017

Language:

english

File:

PDF, 5.88 MB

english, 2017

4

Remarkably effective and simple syntheses of enantiomerically pure secondary carbinols from achiral ketones

E.J. Corey, Xue-Min Cheng, Karlene A. Cimprich, Sepehr Sarshar

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 279 KB

english, 1991

5

1-Mesityl-2,2,2-trifluoroethanol, an outstanding new chiral controller for catalyzed diels-alder reactions

E.J. Corey, Xue-Min Cheng, Karlene A. Cimprich

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 292 KB

english, 1991

6

Enantioselective routes to chiral benzylic thiols, sulfinic esters and sulfonic acids illustrated by the 1-phenylethyl series

E.J. Corey, Karlene A. Cimprich

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 341 KB

english, 1992

7

Checkpoint recovery after DNA damage: a rolling stop for CDKs

Duursma, Anja M, Cimprich, Karlene A

Journal:

Year:

2010

Language:

english

File:

PDF, 170 KB

english, 2010

8

DNA damage tolerance: when it's OK to make mistakes

Chang, Debbie J, Cimprich, Karlene A

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 626 KB

english, 2009

9

ATR: an essential regulator of genome integrity

Cimprich, Karlene A., Cortez, David

Journal:

Nature Reviews Molecular Cell Biology

Year:

2008

Language:

english

File:

PDF, 528 KB

english, 2008

10

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase η on ATR checkpoint signaling

Bomgarden, Ryan D, Lupardus, Patrick J, Soni, Deena V, Yee, Muh-Ching, Ford, James M, Cimprich, Karlene A

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 236 KB

english, 2006

11

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase η on ATR checkpoint signaling

Bomgarden, Ryan D, Lupardus, Patrick J, Soni, Deena V, Yee, Muh-Ching, Ford, James M, Cimprich, Karlene A

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 40 KB

english, 2006

12

The ATR pathway: Fine-tuning the fork

Renee D. Paulsen, Karlene A. Cimprich

Journal:

Year:

2007

Language:

english

File:

PDF, 1.16 MB

english, 2007

13

Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint

Mohammad Hekmat-Nejad, Zhongsheng You, Muh-ching Yee, John W Newport, Karlene A Cimprich

Journal:

Current Biology

Year:

2000

Language:

english

File:

PDF, 389 KB

english, 2000

14

Fragile Sites: Breaking up over a Slowdown

Karlene A. Cimprich

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 101 KB

english, 2003

15

ATR Kinase Activity Regulates the Intranuclear Translocation of ATR and RPA following Ionizing Radiation

Sharon M. Barr, Cindy G. Leung, Elbert E. Chang, Karlene A. Cimprich

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 245 KB

english, 2003

16

Highly Enantioselective Alkynylation of Aldehydes Promoted by Chiral Oxazaborolidines

Corey, E. J., Cimprich, Karlene A.

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 278 KB

english, 1994

17

Checkpoint Adaptation: Molecular Mechanisms Uncovered

Patrick J. Lupardus, Karlene A. Cimprich

Journal:

Year:

2004

Language:

english

File:

PDF, 80 KB

english, 2004

18

A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

Renee D. Paulsen, Deena V. Soni, Roy Wollman, Angela T. Hahn, Muh-Ching Yee, Anna Guan, Jayne A. Hesley, Steven C. Miller, Evan F. Cromwell, David E. Solow-Cordero, Tobias Meyer, Karlene A. Cimprich

Journal:

Year:

2009

Language:

english

File:

PDF, 1.72 MB

english, 2009

19

SHPRH and HLTF Act in a Damage-Specific Manner to Coordinate Different Forms of Postreplication Repair and Prevent Mutagenesis

Jia-Ren Lin, Michelle K. Zeman, Jia-Yun Chen, Muh-Ching Yee, Karlene A. Cimprich

Journal:

Year:

2011

Language:

english

File:

PDF, 1.55 MB

english, 2011

20

A Two-Dimensional ERK-AKT Signaling Code for an NGF-Triggered Cell-Fate Decision

Jia-Yun Chen, Jia-Ren Lin, Karlene A. Cimprich, Tobias Meyer

Journal:

Year:

2012

Language:

english

File:

PDF, 2.38 MB

english, 2012

21

Analyzing the ATR-mediated checkpoint using Xenopus egg extracts

Patrick J. Lupardus, Christopher Van, Karlene A. Cimprich

Journal:

Year:

2007

Language:

english

File:

PDF, 576 KB

english, 2007

22

Enforced Proximity in the Function of a Famous Scaffold

James E Ferrell Jr., Karlene A Cimprich

Journal:

Year:

2003

Language:

english

File:

PDF, 78 KB

english, 2003

23

An ATR- and Cdc7-Dependent DNA Damage Checkpoint that Inhibits Initiation of DNA Replication

Vincenzo Costanzo, David Shechter, Patrick J Lupardus, Karlene A Cimprich, Max Gottesman, Jean Gautier

Journal:

Year:

2003

Language:

english

File:

PDF, 361 KB

english, 2003

24

A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment

Duursma, Anja M., Driscoll, Robert, Elias, Josh E., Cimprich, Karlene A.

Journal:

Year:

2013

Language:

english

File:

PDF, 841 KB

english, 2013

25

The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability

Hamperl, Stephan, Cimprich, Karlene A.

Journal:

Year:

2014

Language:

english

File:

PDF, 3.01 MB

english, 2014

26

Finally, Polyubiquitinated PCNA Gets Recognized

Zeman, Michelle K., Cimprich, Karlene A.

Journal:

Year:

2012

Language:

english

File:

PDF, 138 KB

english, 2012

27

cDNA Cloning and Gene Mapping of a Candidate Human Cell Cycle Checkpoint Protein

Karlene A. Cimprich, Tae Bum Shin, Curtis T. Keith and Stuart L. Schreiber

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.22 MB

english, 1996

28

Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability

Sollier, Julie, Stork, Caroline Townsend, García-Rubio, María L., Paulsen, Renee D., Aguilera, Andrés, Cimprich, Karlene A.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.02 MB

english, 2014

29

Breaking bad: R-loops and genome integrity

Sollier, Julie, Cimprich, Karlene A.

Journal:

Trends in Cell Biology

Year:

2015

Language:

english

File:

PDF, 551 KB

english, 2015

30

HLTF’s Ancient HIRAN Domain Binds 3′ DNA Ends to Drive Replication Fork Reversal

Kile, Andrew C., Chavez, Diana A., Bacal, Julien, Eldirany, Sherif, Korzhnev, Dmitry M., Bezsonova, Irina, Eichman, Brandt F., Cimprich, Karlene A.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.26 MB

english, 2015

31

Probing ATR Activation with Model DNA Templates

Cimprich, Karlene A.

Journal:

Year:

2007

Language:

english

File:

PDF, 572 KB

english, 2007

32

Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells

Hess, Gaelen T, Frésard, Laure, Han, Kyuho, Lee, Cameron H, Li, Amy, Cimprich, Karlene A, Montgomery, Stephen B, Bassik, Michael C

Journal:

Year:

2016

Language:

english

File:

PDF, 2.91 MB

english, 2016

33

The essential kinase ATR: ensuring faithful duplication of a challenging genome

Saldivar, Joshua C., Cortez, David, Cimprich, Karlene A.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2017

Language:

english

File:

PDF, 724 KB

english, 2017

34

Publisher correction: The essential kinase ATR: ensuring faithful duplication of a challenging genome.

Saldivar, Joshua C., Cortez, David, Cimprich, Karlene A.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2017

File:

PDF, 53 KB

2017

35

Faulty replication can sting

Crossley, Madzia P., Cimprich, Karlene A.

Journal:

Year:

2018

Language:

english

File:

PDF, 4.85 MB

english, 2018